Blister Grafting is an effective treatment procedure that is undertaken for treating vitiligo. In this
form of treatment, suction is used for obtaining very thin skin grafts by causing a split at the dermo-epidermal junction. Certain areas like lips and areola respond well to suction blister grafting.
In this process, thin layers of epidermal grafts are obtained from a donor site by providing
negative suction on limited areas.
• The graft that is obtained is then transplanted onto the recipient site that is the dermabraded
vitiliginous area, depending on the size and site of the lesion.
• The graft can fall off within a period, ranging from seven days to ten days.
• Excellent cosmetic results.
• Lower chances of scarring.
DISADVANTAGES OF BLISTER GRAFTING
• Time-consuming
• Not suitable for larger areas
NCES) grafting in Vitiligo Involves separating skin cells from normal
skin and transplanting on white spots as a cell suspension after
removal of upper layer of skin superficially. It is done as a day care
procedure.
Procedure
• Local anaesthetic cream is applied over the donar site(outer sides of
thigh ). Thin split thickness graft is taken from the donar area using
hand dermatome.
• The skin samples are treated with trypsin to separate the epidermal- dermal layers and later cell to cell adhesion is loosened, followed by
vigorous mechanical dissociation in plasma of the patient.
• The melanocytes are harvested as an autologous melanocyte rich cell
suspension is then transplanted to the recipient area that had been
superficially dermabraded. The area is covered with dressing for5
days
The cell suspension usually dries and falls off over a week
span.Repigmentation is noted 3 to 6 months post surgery.
• Can I stop phototherapy after surgery?
• Phototherapy is needed along with medication post surgery for faster
and better result outcome.
• ADVANTAGE –
• Help in treating larger area
• Simple and short day care procedure
Dr. Prema cleared my acne completely with her expert care. My skin feels radiant, and I’ve regained confidence. Truly the best dermatologist in Bangalore!
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